Molecular characterization of community-associated methicillin-resistant Staphylococcus aureus from pet dogs.
Zoonoses Public Health
; 67(3): 222-230, 2020 05.
Article
en En
| MEDLINE
| ID: mdl-31867885
ABSTRACT
Community-associated methicillin-resistant Staphylococcus aureus (MRSA) is a serious public health concern and in Australia, one that disproportionately affects Aboriginal people. Paralleling MRSA in human medicine, methicillin-resistant S. pseudintermedius (MRSP) is an increasingly prevalent pathogen in veterinary medicine. We aimed to characterize the carriage of MRSA and MRSP in dogs and cats from predominantly Aboriginal communities in a very remote region of New South Wales (NSW), Australia. Pets (303 dogs and 80 cats) were recruited from six communities in western NSW. Three swabs were collected from each animal (anterior nares, oropharynx and perineum) and from skin lesions or wounds (if present) and cultured on selective media for methicillin-resistant staphylococci. Human host-adapted community-associated MRSA representing four multilocus sequence types (ST1-IV, ST5-IV, ST72-IV, ST93-IV) were isolated from eight dogs (prevalence 2.6%, 95% confidence interval 1.3%-5.1%). Two ST5-IV isolates from a single dog were phenotypically trimethoprim-resistant, harbouring trimethoprim-resistant gene dfrG within the SCCmec type IVo mobile genetic element. MRSA was not isolated from any cats and MRSP was not isolated from any dogs or cats. This study estimated a high prevalence of human host-adapted community-associated MRSA carriage in dogs despite an absence of MRSP. This suggests MRSA carried by dogs in remote NSW originate from human hosts. The cycle of transmission between people, dogs and common environmental sources warrants further investigation. To our knowledge, this is the first report of trimethoprim-resistant ST5-IV in eastern Australia and the first report of trimethoprim-resistant ST5-IV from a dog.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones Estafilocócicas
/
Reservorios de Enfermedades
/
Infecciones Comunitarias Adquiridas
/
Enfermedades de los Perros
/
Staphylococcus aureus Resistente a Meticilina
Tipo de estudio:
Risk_factors_studies
Límite:
Animals
País/Región como asunto:
Oceania
Idioma:
En
Revista:
Zoonoses Public Health
Asunto de la revista:
MEDICINA VETERINARIA
/
SAUDE PUBLICA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Australia