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Metabolic profiling of tyrosine kinase inhibitor nintedanib using metabolomics.
Zhou, Zi-Meng; Wang, Yi-Kun; Yan, Dong-Mei; Fang, Jian-He; Xiao, Xue-Rong; Zhang, Ting; Cheng, Yan; Xu, Kang-Ping; Li, Fei.
Afiliación
  • Zhou ZM; College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
  • Wang YK; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Yan DM; College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
  • Fang JH; College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
  • Xiao XR; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
  • Zhang T; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Cheng Y; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China. Electronic address: chengyan2012@gmail.com.
  • Xu KP; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, China.
  • Li F; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China. Electronic address: lifeib@mail.kib.ac.cn.
J Pharm Biomed Anal ; 180: 113045, 2020 Feb 20.
Article en En | MEDLINE | ID: mdl-31887668
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microsomas Hepáticos / Inhibidores de Proteínas Quinasas / Metabolómica / Indoles Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: J Pharm Biomed Anal Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microsomas Hepáticos / Inhibidores de Proteínas Quinasas / Metabolómica / Indoles Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: J Pharm Biomed Anal Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido