[Effect of anabol on the functional activity indices of mononuclear phagocytes]. / Vliianie anabola na nekotorye pokazateli funktsional'noi aktivnosti mononuklearnykh fagotsitov.
Antibiot Khimioter
; 33(7): 524-7, 1988 Jul.
Article
en Ru
| MEDLINE
| ID: mdl-3190348
Anabol is a biopolymer from the complex of components extracted from the surface layer of the Lactobacillus bulgaricus cell wall. Its effect on certain indices of the functional activity of mononuclear phagocytes was studied. Administration of the preparation in a dose of 20 mg/kg 24 hours before the investigation resulted in lowering of the stain half-life in the general blood flow and increasing of the fibronectin levels in blood plasma of rats. Activation of the metabolic activity estimated by nitroblue tetrazolium test as well as resident cells and induced macrophages was observed. 24 hours after the anabol administration there was noted a marked increase in the pool of the precursors of granulocytes and macrophages, the stimulating effect being preserved for up to 3 days. The results showed that anabol had an effect on various elements of the system of mononuclear phagocytes. It may be useful in complex therapy aimed at increasing the host resistance to diverse toxic substances and bacterial infection.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Productos Biológicos
/
Monocitos
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
Ru
Revista:
Antibiot Khimioter
Asunto de la revista:
TERAPIA POR MEDICAMENTOS
Año:
1988
Tipo del documento:
Article
Pais de publicación:
Rusia