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Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators.
Malinak, David; Dolezal, Rafael; Hepnarova, Vendula; Hozova, Miroslava; Andrys, Rudolf; Bzonek, Petr; Racakova, Veronika; Korabecny, Jan; Gorecki, Lukas; Mezeiova, Eva; Psotka, Miroslav; Jun, Daniel; Kuca, Kamil; Musilek, Kamil.
Afiliación
  • Malinak D; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic.
  • Dolezal R; Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.
  • Hepnarova V; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic.
  • Hozova M; Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.
  • Andrys R; Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.
  • Bzonek P; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic.
  • Racakova V; Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.
  • Korabecny J; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic.
  • Gorecki L; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic.
  • Mezeiova E; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic.
  • Psotka M; Faculty of Informatics and Management, Center for Basic and Applied Research, University of Hradec Kralove, Hradec Kralove, Czech Republic.
  • Jun D; Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.
  • Kuca K; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic.
  • Musilek K; Biomedical Research Centre, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic.
J Enzyme Inhib Med Chem ; 35(1): 478-488, 2020 Dec.
Article en En | MEDLINE | ID: mdl-31910701
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetilcolinesterasa / Butirilcolinesterasa / Reactivadores de la Colinesterasa / Isoquinolinas Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetilcolinesterasa / Butirilcolinesterasa / Reactivadores de la Colinesterasa / Isoquinolinas Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Reino Unido