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Analyses of the oncogenic BRAFD594G variant reveal a kinase-independent function of BRAF in activating MAPK signaling.
Cope, Nicholas J; Novak, Borna; Liu, Zhiwei; Cavallo, Maria; Gunderwala, Amber Y; Connolly, Matthew; Wang, Zhihong.
Afiliación
  • Cope NJ; Department of Chemistry & Biochemistry, University of the Sciences, Philadelphia, Pennsylvania 19104.
  • Novak B; Department of Chemistry & Biochemistry, University of the Sciences, Philadelphia, Pennsylvania 19104.
  • Liu Z; Department of Chemistry & Biochemistry, University of the Sciences, Philadelphia, Pennsylvania 19104.
  • Cavallo M; Department of Chemistry & Biochemistry, University of the Sciences, Philadelphia, Pennsylvania 19104.
  • Gunderwala AY; Department of Chemistry & Biochemistry, University of the Sciences, Philadelphia, Pennsylvania 19104.
  • Connolly M; Department of Chemistry & Biochemistry, University of the Sciences, Philadelphia, Pennsylvania 19104.
  • Wang Z; Department of Chemistry & Biochemistry, University of the Sciences, Philadelphia, Pennsylvania 19104. Electronic address: z.wang@usciences.edu.
J Biol Chem ; 295(8): 2407-2420, 2020 02 21.
Article en En | MEDLINE | ID: mdl-31929109

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sistema de Señalización de MAP Quinasas / Proteínas Proto-Oncogénicas B-raf / Mutación Límite: Humans Idioma: En Revista: J Biol Chem Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sistema de Señalización de MAP Quinasas / Proteínas Proto-Oncogénicas B-raf / Mutación Límite: Humans Idioma: En Revista: J Biol Chem Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos