Aminooxyacetic acid attenuates post-infarct cardiac dysfunction by balancing macrophage polarization through modulating macrophage metabolism in mice.

Zhao, Pei; Zhou, Wenjing; Zhang, Yanxia; Li, Jingjing; Zhao, Ye; Pan, Lihua; Shen, Zhenya; Chen, Weiqian; Hui, Jie

Zhao, Pei; Zhou, Wenjing; Zhang, Yanxia; Li, Jingjing; Zhao, Ye; Pan, Lihua; Shen, Zhenya; Chen, Weiqian; Hui, Jie.

Afiliación

Zhao P; Department of Cardiovascular Surgery, The First Affiliated Hospital of Soochow University & Institute for Cardiovascular Science, Soochow University, Suzhou, China.
Zhou W; Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Zhang Y; Department of Cardiology, The Affiliated Hospital of Yangzhou University, Yangzhou, China.
Li J; Department of Cardiovascular Surgery, The First Affiliated Hospital of Soochow University & Institute for Cardiovascular Science, Soochow University, Suzhou, China.
Zhao Y; Department of Cardiovascular Surgery, The First Affiliated Hospital of Soochow University & Institute for Cardiovascular Science, Soochow University, Suzhou, China.
Pan L; Department of Cardiovascular Surgery, The First Affiliated Hospital of Soochow University & Institute for Cardiovascular Science, Soochow University, Suzhou, China.
Shen Z; Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Chen W; Department of Cardiovascular Surgery, The First Affiliated Hospital of Soochow University & Institute for Cardiovascular Science, Soochow University, Suzhou, China.
Hui J; Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, China.

J Cell Mol Med ; 24(4): 2593-2609, 2020 02.

Article en En | MEDLINE | ID: mdl-31930778

Asunto(s)

Ácido Aminooxiacético/farmacología; Cardiopatías/tratamiento farmacológico; Corazón/efectos de los fármacos; Macrófagos/efectos de los fármacos; Macrófagos/metabolismo; Animales; Antiinflamatorios/farmacología; Caspasa 1/metabolismo; Cardiopatías/metabolismo; Interleucina-1beta/metabolismo; Interleucina-6/metabolismo; Masculino; Ratones; Ratones Endogámicos C57BL; Infarto del Miocardio/tratamiento farmacológico; Infarto del Miocardio/metabolismo; Miocardio/metabolismo; Proteína con Dominio Pirina 3 de la Familia NLR/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo; Remodelación Ventricular/efectos de los fármacos

Palabras clave

NLRP3; aminooxyacetic acid; macrophage polarization; metabolic reprogramming; myocardial infarction

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Aminooxiacético / Corazón / Cardiopatías / Macrófagos Límite: Animals Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google