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A Four-Chemokine Signature Is Associated with a T-cell-Inflamed Phenotype in Primary and Metastatic Pancreatic Cancer.
Romero, Joan M; Grünwald, Barbara; Jang, Gun-Ho; Bavi, Prashant P; Jhaveri, Aaditeya; Masoomian, Mehdi; Fischer, Sandra E; Zhang, Amy; Denroche, Robert E; Lungu, Ilinca M; De Luca, Angela; Bartlett, John M S; Xu, Jing; Li, Niandong; Dhaliwal, Sharon; Liang, Sheng-Ben; Chadwick, Dianne; Vyas, Foram; Bronsert, Peter; Khokha, Rama; McGaha, Tracy L; Notta, Faiyaz; Ohashi, Pamela S; Done, Susan J; O'Kane, Grainne M; Wilson, Julie M; Knox, Jennifer J; Connor, Ashton; Wang, Yifan; Zogopoulos, George; Gallinger, Steven.
Afiliación
  • Romero JM; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
  • Grünwald B; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Jang GH; Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Bavi PP; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Jhaveri A; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
  • Masoomian M; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Fischer SE; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Zhang A; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada.
  • Denroche RE; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
  • Lungu IM; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • De Luca A; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada.
  • Bartlett JMS; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Xu J; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Li N; Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Dhaliwal S; Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Liang SB; Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Chadwick D; Drug Development Program Biomarker Laboratory, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Vyas F; UHN Biobank, University Health Network, Toronto, Ontario, Canada.
  • Bronsert P; UHN Biobank, University Health Network, Toronto, Ontario, Canada.
  • Khokha R; UHN Biobank, University Health Network, Toronto, Ontario, Canada.
  • McGaha TL; UHN Biobank, University Health Network, Toronto, Ontario, Canada.
  • Notta F; Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Ohashi PS; Tumorbank Comprehensive Cancer Center Freiburg, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Done SJ; Institute for Surgical Pathology, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
  • O'Kane GM; Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Wilson JM; Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Knox JJ; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
  • Connor A; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Wang Y; Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Zogopoulos G; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
  • Gallinger S; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Clin Cancer Res ; 26(8): 1997-2010, 2020 04 15.
Article en En | MEDLINE | ID: mdl-31964786
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Biomarcadores de Tumor / Linfocitos T CD8-positivos / Quimiocina CCL5 / Quimiocina CCL4 / Quimiocina CXCL9 / Quimiocina CXCL10 / Neoplasias Hepáticas Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Biomarcadores de Tumor / Linfocitos T CD8-positivos / Quimiocina CCL5 / Quimiocina CCL4 / Quimiocina CXCL9 / Quimiocina CXCL10 / Neoplasias Hepáticas Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos