Assessment of a split-bolus computed tomographic enterography technique for simultaneous evaluation of the intestinal wall and mesenteric vasculature of dogs.

ABSTRACT

OBJECTIVE: To investigate the diagnostic usefulness of split-bolus CT enterography in dogs. ANIMALS 6 healthy Beagles. PROCEDURES CT enterography was performed in all dogs in a nonrandomized crossover study design involving 3 techniques a dual-phase technique and 2 techniques involving splitting of the administered contrast agent dose (ie, split technique and split-bolus tracking technique). For the 2 techniques involving dose splitting (ie, split CT enterography), contrast agent was injected twice, with the first injection consisting of 60% of the total dose, followed by injection of the remaining 40%. Then, a single set of CT images was obtained when the arterial and venous phases matched (dual-phase and split techniques) or when enhancement of the abdominal aorta reached 100 HU (split-bolus tracking technique). Enhancement of the intestinal wall and mesenteric vessels was assessed qualitatively and quantitatively. RESULTS: The total number of images required for interpretation was significantly lower for the split technique than for the dual-phase technique. The amount of time needed to complete CT enterography was significantly less for the split-bolus tracking technique than for the other 2 techniques. For all 3 techniques, adequate contrast enhancement of the mesenteric vessels and intestinal wall was achieved. The split technique provided contrast enhancement of the intestinal wall and mesenteric vessels similar to that provided with the dual-phase technique, whereas contrast enhancement of these structures was lowest for the split-bolus tracking technique. CONCLUSIONS AND CLINICAL RELEVANCE Split-bolus CT enterography at a contrast agent allocation ratio of 6040 enabled simultaneous evaluation of the enhanced intestine wall and mesenteric vessels and yielded image quality similar to that of dual-phase CT enterography in healthy dogs.