Twenty years with diabetes and amputations: a retrospective population-based cohort study.
Diabet Med
; 37(12): 2098-2108, 2020 12.
Article
en En
| MEDLINE
| ID: mdl-31990417
ABSTRACT
AIM:
To investigate the trends in non-traumatic lower limb amputation in people with and without diabetes.METHODS:
From the Danish National Patient Register, all people with either type 1 or type 2 diabetes (n = 462 743) as well as a group of people without diabetes from the general population (n = 1 388 886) were identified and separated into three groups based on diabetes type. Among these, 17 265 amputations were identified between 1997 and 2017 and stratified into trans-femoral amputations, trans-tibial amputations and amputations below the ankle using surgical codes. Annual changes were described using least-squares linear regression.RESULTS:
The yearly mean decrease in incidence rate of amputation per 1000 person-years was -0.032 [95% CI -0.062, -0.001], -0.022 [-0.032, -0.012] and -0.006 [-0.009, -0.003] for trans-femoral amputation, -0.072 [-0.093, -0.052], -0.090 [-0.102, -0.078] and -0.015 [-0.016, -0.013] for trans-tibial amputation, and -0.055 [-0.080, -0.020], -0.075 [-0.090, -0.060] and -0.011 [-0.014, -0.007] for amputation below the ankle in people with type 1 diabetes, people with type 2 diabetes and people without diabetes, respectively.CONCLUSIONS:
Over recent decades, the incidence of amputation has decreased significantly in people with diabetes and in the general population without diabetes.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Extremidad Inferior
/
Diabetes Mellitus Tipo 1
/
Diabetes Mellitus Tipo 2
/
Enfermedad Arterial Periférica
/
Amputación Quirúrgica
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Diabet Med
Asunto de la revista:
ENDOCRINOLOGIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Dinamarca