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Polymeric modification of gemcitabine via cyclic acetal linkage for enhanced anticancer potency with negligible side effects.
Takemoto, Hiroyasu; Inaba, Takanori; Nomoto, Takahiro; Matsui, Makoto; Liu, Xiaomeng; Toyoda, Masahiro; Honda, Yuto; Taniwaki, Kaori; Yamada, Naoki; Kim, Junhyun; Tomoda, Keishiro; Nishiyama, Nobuhiro.
Afiliación
  • Takemoto H; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-11, 4259, Nagatsuta, Midori-Ku, Yokohama, Kanagawa, 226-8503, Japan. Electronic address: takemoto@res.titech.ac.jp.
  • Inaba T; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-11, 4259, Nagatsuta, Midori-Ku, Yokohama, Kanagawa, 226-8503, Japan.
  • Nomoto T; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-11, 4259, Nagatsuta, Midori-Ku, Yokohama, Kanagawa, 226-8503, Japan.
  • Matsui M; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-11, 4259, Nagatsuta, Midori-Ku, Yokohama, Kanagawa, 226-8503, Japan.
  • Liu X; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-11, 4259, Nagatsuta, Midori-Ku, Yokohama, Kanagawa, 226-8503, Japan.
  • Toyoda M; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-11, 4259, Nagatsuta, Midori-Ku, Yokohama, Kanagawa, 226-8503, Japan.
  • Honda Y; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-11, 4259, Nagatsuta, Midori-Ku, Yokohama, Kanagawa, 226-8503, Japan.
  • Taniwaki K; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-11, 4259, Nagatsuta, Midori-Ku, Yokohama, Kanagawa, 226-8503, Japan.
  • Yamada N; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-11, 4259, Nagatsuta, Midori-Ku, Yokohama, Kanagawa, 226-8503, Japan.
  • Kim J; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-11, 4259, Nagatsuta, Midori-Ku, Yokohama, Kanagawa, 226-8503, Japan.
  • Tomoda K; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-11, 4259, Nagatsuta, Midori-Ku, Yokohama, Kanagawa, 226-8503, Japan.
  • Nishiyama N; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-11, 4259, Nagatsuta, Midori-Ku, Yokohama, Kanagawa, 226-8503, Japan. Electronic address: nishiyama.n.ad@m.titech.ac.jp.
Biomaterials ; 235: 119804, 2020 03.
Article en En | MEDLINE | ID: mdl-31991339
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Acetales Límite: Animals Idioma: En Revista: Biomaterials Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Acetales Límite: Animals Idioma: En Revista: Biomaterials Año: 2020 Tipo del documento: Article