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Hydroxychloroquine suppresses lung tumorigenesis via inducing FoxO3a nuclear translocation through STAT3 inactivation.
Lyu, Xin; Zeng, Lizhong; Zhang, Hua; Ke, Yue; Liu, Xuan; Zhao, Nannan; Yuan, Jingyan; Chen, Guoan; Yang, Shuanying.
Afiliación
  • Lyu X; Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Xi'an Jiaotong University, No. 157, Xiwu Road, Xincheng District, Xi'an 710004, Shaanxi, PR China.
  • Zeng L; Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Xi'an Jiaotong University, No. 157, Xiwu Road, Xincheng District, Xi'an 710004, Shaanxi, PR China.
  • Zhang H; Department of Obstetrics and Gynecology, Second Affiliated Hospital, Xi'an Jiaotong University, No. 157, Xiwu Road, Xincheng District, Xi'an 710004, Shaanxi, PR China.
  • Ke Y; Department of Radiation Oncology, Second Affiliated Hospital, Xi'an Jiaotong University, No. 157, Xiwu Road, Xincheng District, Xi'an 710004, Shaanxi, PR China.
  • Liu X; Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Xi'an Jiaotong University, No. 157, Xiwu Road, Xincheng District, Xi'an 710004, Shaanxi, PR China.
  • Zhao N; Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Xi'an Jiaotong University, No. 157, Xiwu Road, Xincheng District, Xi'an 710004, Shaanxi, PR China.
  • Yuan J; Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Xi'an Jiaotong University, No. 157, Xiwu Road, Xincheng District, Xi'an 710004, Shaanxi, PR China.
  • Chen G; School of Medicine, Southern University of Science and Technology, No. 1088, Xueyuan Road, Nanshan District, Shenzhen 518055, Guangdong, China.
  • Yang S; Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Xi'an Jiaotong University, No. 157, Xiwu Road, Xincheng District, Xi'an 710004, Shaanxi, PR China. Electronic address: yangshuangying66@163.com.
Life Sci ; 246: 117366, 2020 Apr 01.
Article en En | MEDLINE | ID: mdl-32001266
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adenocarcinoma / Factor de Transcripción STAT3 / Proteína Forkhead Box O3 / Hidroxicloroquina / Neoplasias Pulmonares / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Life Sci Año: 2020 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adenocarcinoma / Factor de Transcripción STAT3 / Proteína Forkhead Box O3 / Hidroxicloroquina / Neoplasias Pulmonares / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Life Sci Año: 2020 Tipo del documento: Article Pais de publicación: Países Bajos