Neonatal hypoglycemia after initiation of late preterm antenatal corticosteroids.
J Perinatol
; 40(9): 1339-1348, 2020 09.
Article
en En
| MEDLINE
| ID: mdl-32060360
ABSTRACT
OBJECTIVE:
To compare the frequency and severity of neonatal hypoglycemia in pregnancies treated with and without late preterm antenatal corticosteroids. STUDYDESIGN:
We conducted a retrospective cohort study of late preterm deliveries at LAC + USC (2015-2018). Neonatal outcomes were compared between pregnancies treated with and without corticosteroids.RESULTS:
93 pregnancies (39.9%) received corticosteroids and 140 (60.1%) did not. Neonates born to women given corticosteroids were more likely to be hypoglycemic (47.3 vs. 29.3%, ORadj 2.25, padj = 0.01). The mean initial glucose (45.6 mg/dL vs. 51.9 mg/dL, p = 0.01) and glucose nadir (39.1 mg/dL vs. 45.4 mg/dL, p < 0.001) were significantly lower if the neonates received corticosteroids. Neonates admitted to the NICU solely for hypoglycemia were more likely to be born to women treated with corticosteroids (ORadj 4.71, padj = 0.01).CONCLUSION:
Administration of late preterm corticosteroids was associated with an increased incidence and severity of neonatal hypoglycemia.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Atención Prenatal
/
Hipoglucemia
Tipo de estudio:
Observational_studies
Límite:
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
J Perinatol
Asunto de la revista:
PERINATOLOGIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Estados Unidos