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Prostaglandin E2 in a TLR3- and 7/8-agonist-based DC maturation cocktail generates mature, cytokine-producing, migratory DCs but impairs antigen cross-presentation to CD8+ T cells.
Gierlich, Philipp; Lex, Veronika; Technau, Antje; Keupp, Anne; Morper, Lorenz; Glunz, Amelie; Sennholz, Hanno; Rachor, Johannes; Sauer, Sascha; Marcu, Ana; Grigoleit, Götz Ulrich; Wölfl, Matthias; Schlegel, Paul G; Eyrich, Matthias.
Afiliación
  • Gierlich P; Laboratory for Stem Cell Processing and Cellular TherapyUniversity Medical Center, Children's Hospital, Würzburg, Germany.
  • Lex V; Laboratory for Stem Cell Processing and Cellular TherapyUniversity Medical Center, Children's Hospital, Würzburg, Germany.
  • Technau A; Laboratory for Stem Cell Processing and Cellular TherapyUniversity Medical Center, Children's Hospital, Würzburg, Germany.
  • Keupp A; Laboratory for Stem Cell Processing and Cellular TherapyUniversity Medical Center, Children's Hospital, Würzburg, Germany.
  • Morper L; Laboratory for Stem Cell Processing and Cellular TherapyUniversity Medical Center, Children's Hospital, Würzburg, Germany.
  • Glunz A; Laboratory for Stem Cell Processing and Cellular TherapyUniversity Medical Center, Children's Hospital, Würzburg, Germany.
  • Sennholz H; Laboratory for Stem Cell Processing and Cellular TherapyUniversity Medical Center, Children's Hospital, Würzburg, Germany.
  • Rachor J; Laboratory for Stem Cell Processing and Cellular TherapyUniversity Medical Center, Children's Hospital, Würzburg, Germany.
  • Sauer S; CU Systems Medicine, University of Würzburg, Würzburg, Germany.
  • Marcu A; Max Delbrück Center for Molecular Medicine (BIMSB/BIH), Berlin, Germany.
  • Grigoleit GU; Department of Immunology, Interfaculty Institute for Cell Biology, University of Tübingen, Tübingen, Germany.
  • Wölfl M; Department of Internal Medicine II, University Medical Center, Würzburg, Germany.
  • Schlegel PG; Laboratory for Stem Cell Processing and Cellular TherapyUniversity Medical Center, Children's Hospital, Würzburg, Germany.
  • Eyrich M; Laboratory for Stem Cell Processing and Cellular TherapyUniversity Medical Center, Children's Hospital, Würzburg, Germany.
Cancer Immunol Immunother ; 69(6): 1029-1042, 2020 Jun.
Article en En | MEDLINE | ID: mdl-32100075

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Dendríticas / Dinoprostona / Presentación de Antígeno / Linfocitos T CD8-positivos / Receptor Toll-Like 3 Límite: Humans Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Dendríticas / Dinoprostona / Presentación de Antígeno / Linfocitos T CD8-positivos / Receptor Toll-Like 3 Límite: Humans Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania