Rare variants and biological pathways identified in treatment-refractory depression.

McClain, Lora Lee; Shaw, Patricia; Sabol, Roisin; Chedia, Anna Maria; Segretti, Anna Maria; Rengasamy, Manivel; Finegold, David N; Pan, Lisa; Peters, David Gerard

McClain, Lora Lee; Shaw, Patricia; Sabol, Roisin; Chedia, Anna Maria; Segretti, Anna Maria; Rengasamy, Manivel; Finegold, David N; Pan, Lisa; Peters, David Gerard.

Afiliación

McClain LL; Department of Psychiatry, Western Psychiatric Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Shaw P; Center for Fetal Medicine, Magee-Womens Research Institute, Pittsburgh, PA, USA.
Sabol R; Department of Psychiatry, Western Psychiatric Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Chedia AM; Center for Fetal Medicine, Magee-Womens Research Institute, Pittsburgh, PA, USA.
Segretti AM; Creative and Performing Arts Magnet, Pittsburgh Public Schools, Pittsburgh, PA, USA.
Rengasamy M; Department of Psychiatry, Western Psychiatric Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Finegold DN; Department of Psychiatry, Western Psychiatric Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Pan L; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.
Peters DG; Department of Psychiatry, Western Psychiatric Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

J Neurosci Res ; 98(7): 1322-1334, 2020 07.

Article en En | MEDLINE | ID: mdl-32128872

Asunto(s)

Biopterinas/análogos & derivados; Carnitina/análogos & derivados; Trastorno Depresivo Resistente al Tratamiento/sangre; Tetrahidrofolatos/sangre; Adolescente; Adulto; Alelos; Biopterinas/sangre; Carnitina/sangre; Simulación por Computador; Trastorno Depresivo Resistente al Tratamiento/genética; Femenino; Predisposición Genética a la Enfermedad; Humanos; Masculino; Fenotipo; Polimorfismo de Nucleótido Simple; Secuenciación del Exoma; Adulto Joven

Palabras clave

gene set enrichment; genetic association; major depressive disorder; treatment-refractory depression; whole exome sequencing

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biopterinas / Carnitina / Tetrahidrofolatos / Trastorno Depresivo Resistente al Tratamiento Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: J Neurosci Res Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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