Improved efficacy, tolerance, safety, and abuse liability profile of the combination of CR4056 and morphine over morphine alone in rodent models.

Sala, Emanuele; Ferrari, Flora; Lanza, Marco; Milia, Chiara; Sabatini, Chiara; Bonazzi, Albino; Comi, Eleonora; Borsi Franchini, Miriam; Caselli, Gianfranco; Rovati, Lucio Claudio

Sala, Emanuele; Ferrari, Flora; Lanza, Marco; Milia, Chiara; Sabatini, Chiara; Bonazzi, Albino; Comi, Eleonora; Borsi Franchini, Miriam; Caselli, Gianfranco; Rovati, Lucio Claudio.

Afiliación

Sala E; Rottapharm Biotech, Monza, Italy.
Ferrari F; PhD program in Neuroscience, University of Milano-Bicocca, Monza, Italy.
Lanza M; Rottapharm Biotech, Monza, Italy.
Milia C; Rottapharm Biotech, Monza, Italy.
Sabatini C; School of Medicine and Surgery, University of Milano - Bicocca, Monza, Italy.
Bonazzi A; Rottapharm Biotech, Monza, Italy.
Comi E; PhD program in Neuroscience, University of Milano-Bicocca, Monza, Italy.
Borsi Franchini M; Rottapharm Biotech, Monza, Italy.
Caselli G; Rottapharm Biotech, Monza, Italy.
Rovati LC; Rottapharm Biotech, Monza, Italy.

Br J Pharmacol ; 177(14): 3291-3308, 2020 07.

Article en En | MEDLINE | ID: mdl-32154915

Asunto(s)

Morfina; Roedores; Analgésicos Opioides/toxicidad; Animales; Tolerancia a Medicamentos; Imidazoles; Morfina/efectos adversos; Quinazolinas; Ratas

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Roedores / Morfina Límite: Animals Idioma: En Revista: Br J Pharmacol Año: 2020 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido

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