Chlorpyrifos-induced cell proliferation in human breast cancer cell lines differentially mediated by estrogen and aryl hydrocarbon receptors and KIAA1363 enzyme after 24 h and 14 days exposure.

Moyano, Paula; García, Jimena; García, José Manuel; Pelayo, Adela; Muñoz-Calero, Pilar; Frejo, María Teresa; Anadon, Maria Jose; Lobo, Margarita; Del Pino, Javier

Chlorpyrifos-induced cell proliferation in human breast cancer cell lines differentially mediated by estrogen and aryl hydrocarbon receptors and KIAA1363 enzyme after 24 h and 14 days exposure.

Moyano, Paula; García, Jimena; García, José Manuel; Pelayo, Adela; Muñoz-Calero, Pilar; Frejo, María Teresa; Anadon, Maria Jose; Lobo, Margarita; Del Pino, Javier.

Afiliación

Moyano P; Department of Pharmacology and Toxicology, Medicine School, Complutense University of Madrid, 28040, Madrid, Spain.
García J; Department of Pharmacology, Health Sciences School, Alfonso X University, 28691, Madrid, Spain.
García JM; Department of Pharmacology and Toxicology, Medicine School, Complutense University of Madrid, 28040, Madrid, Spain.
Pelayo A; Department of Legal Medicine, Psychiatry and Pathology, Medicine School, Complutense University of Madrid, 28040, Madrid, Spain.
Muñoz-Calero P; Alborada Foundation, 28690, Brunete, Spain.
Frejo MT; Department of Pharmacology and Toxicology, Medicine School, Complutense University of Madrid, 28040, Madrid, Spain.
Anadon MJ; Department of Legal Medicine, Psychiatry and Pathology, Medicine School, Complutense University of Madrid, 28040, Madrid, Spain.
Lobo M; Department of Pharmacology and Toxicology, Medicine School, Complutense University of Madrid, 28040, Madrid, Spain.
Del Pino J; Department of Pharmacology and Toxicology, Medicine School, Complutense University of Madrid, 28040, Madrid, Spain. Electronic address: jdelpino@pdi.ucm.es.

Chemosphere ; 251: 126426, 2020 Jul.

Article en En | MEDLINE | ID: mdl-32171938

Asunto(s)

Cloropirifos/toxicidad; Insecticidas/toxicidad; Receptores de Hidrocarburo de Aril/metabolismo; Esterol Esterasa/metabolismo; Proliferación Celular/efectos de los fármacos; Cloropirifos/análogos & derivados; Citocromo P-450 CYP1A1/metabolismo; Citocromo P-450 CYP1B1; Receptor alfa de Estrógeno; Estrógenos/farmacología; Humanos; Células MCF-7; Células Tumorales Cultivadas

Palabras clave

AhR; CYP1A1; Chlorpyrifos; ER; KIAA163; MCF-7; MDA-MB-231

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esterol Esterasa / Receptores de Hidrocarburo de Aril / Cloropirifos / Insecticidas Límite: Humans Idioma: En Revista: Chemosphere Año: 2020 Tipo del documento: Article País de afiliación: España

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