Loss of PP2A Disrupts the Retention of Radial Glial Progenitors in the Telencephalic Niche to Impair the Generation for Late-Born Neurons During Cortical Development.

Huang, Chaoli; Liu, Tingting; Wang, Qihui; Hou, Weikang; Zhou, Cuihua; Song, Zeyuan; Shi, Yun Stone; Gao, Xiang; Chen, Guiquan; Yin, Zhenyu; Hu, Yimin

Loss of PP2A Disrupts the Retention of Radial Glial Progenitors in the Telencephalic Niche to Impair the Generation for Late-Born Neurons During Cortical Development.

Huang, Chaoli; Liu, Tingting; Wang, Qihui; Hou, Weikang; Zhou, Cuihua; Song, Zeyuan; Shi, Yun Stone; Gao, Xiang; Chen, Guiquan; Yin, Zhenyu; Hu, Yimin.

Afiliación

Huang C; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Liu T; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Wang Q; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Hou W; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Zhou C; Department of Anesthesiology, The Second Affiliated Changzhou People's Hospital of Nanjing Medical University, Changzhou 213000, China.
Song Z; Department of Anesthesiology, The Second Affiliated Changzhou People's Hospital of Nanjing Medical University, Changzhou 213000, China.
Shi YS; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Gao X; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Chen G; State Key Laboratory of Pharmaceutical Biotechnology, MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Institute for Brain Sciences, Nanjing University, Nanjing 210061, China.
Yin Z; Department of Geriatric, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China.
Hu Y; Department of Anesthesiology, The Second Affiliated Changzhou People's Hospital of Nanjing Medical University, Changzhou 213000, China.

Cereb Cortex ; 30(7): 4183-4196, 2020 06 01.

Article en En | MEDLINE | ID: mdl-32186707

Asunto(s)

Células Ependimogliales/citología; Neocórtex/embriología; Células-Madre Neurales/citología; Proteína Fosfatasa 2/genética; Uniones Adherentes/metabolismo; Animales; Cadherinas/metabolismo; Movimiento Celular; Proliferación Celular/genética; Células Ependimogliales/metabolismo; Ratones; Ratones Noqueados; Células-Madre Neurales/metabolismo; Proteína Fosfatasa 2/metabolismo; Telencéfalo/citología

Palabras clave

cortical development; protein phosphatase 2A; radial glial progenitor; stem cell niche; ventricular zone

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neocórtex / Proteína Fosfatasa 2 / Células-Madre Neurales / Células Ependimogliales Límite: Animals Idioma: En Revista: Cereb Cortex Asunto de la revista: CEREBRO Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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