Effects of molecular weight and structural conformation of multivalent-based elastin-like polypeptides on tumor accumulation and tissue biodistribution.

Sarangthem, Vijaya; Seo, Bo-Yeon; Yi, Aena; Lee, Young-Jin; Cheon, Sun-Ha; Kim, Sang Kyoon; Singh, Thoudam Debraj; Lee, Byung-Heon; Park, Rang-Woon

Sarangthem, Vijaya; Seo, Bo-Yeon; Yi, Aena; Lee, Young-Jin; Cheon, Sun-Ha; Kim, Sang Kyoon; Singh, Thoudam Debraj; Lee, Byung-Heon; Park, Rang-Woon.

Afiliación

Sarangthem V; Department of Biochemistry and Cell Biology, School of Medicine, and Cell & Matrix Research Institute, Kyungpook National University, Daegu 41944, Republic of Korea.
Seo BY; Department of Pathology, All India Institute of Medical Sciences, New Delhi-110029, India.
Yi A; Department of Biochemistry and Cell Biology, School of Medicine, and Cell & Matrix Research Institute, Kyungpook National University, Daegu 41944, Republic of Korea.
Lee YJ; Department of Biochemistry and Cell Biology, School of Medicine, and Cell & Matrix Research Institute, Kyungpook National University, Daegu 41944, Republic of Korea.
Cheon SH; Department of Biochemistry and Cell Biology, School of Medicine, and Cell & Matrix Research Institute, Kyungpook National University, Daegu 41944, Republic of Korea.
Kim SK; Department of Biochemistry and Cell Biology, School of Medicine, and Cell & Matrix Research Institute, Kyungpook National University, Daegu 41944, Republic of Korea.
Singh TD; Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Cheombok, Daegu, 41061, Republic of Korea.
Lee BH; Department of Medical Oncology Lab., All India Institute of Medical Sciences, New Delhi-110029, India.
Park RW; Department of Biochemistry and Cell Biology, School of Medicine, and Cell & Matrix Research Institute, Kyungpook National University, Daegu 41944, Republic of Korea.

Nanotheranostics ; 4(2): 57-70, 2020.

Article en En | MEDLINE | ID: mdl-32190533

Asunto(s)

Antineoplásicos; Portadores de Fármacos; Elastina; Neoplasias/metabolismo; Péptidos; Animales; Antineoplásicos/química; Antineoplásicos/metabolismo; Antineoplásicos/farmacocinética; Línea Celular Tumoral; Portadores de Fármacos/química; Portadores de Fármacos/metabolismo; Portadores de Fármacos/farmacocinética; Elastina/química; Elastina/metabolismo; Elastina/farmacocinética; Femenino; Humanos; Ratones Endogámicos BALB C; Micelas; Peso Molecular; Péptidos/química; Péptidos/metabolismo; Péptidos/farmacocinética; Conformación Proteica; Receptores de Interleucina-4/química; Receptores de Interleucina-4/metabolismo; Distribución Tisular; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

ELP; IL-4 receptor; biodistribution; multivalent; size-dependent; tumor targeting

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos / Portadores de Fármacos / Elastina / Neoplasias / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nanotheranostics Año: 2020 Tipo del documento: Article Pais de publicación: Australia

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