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Plant Based Bioreactors of Recombinant Cytokines (Review).
Burlakovskiy, M S; Yemelyanov, V V; Lutova, L A.
Afiliación
  • Burlakovskiy MS; Biology Faculty, St. Petersburg State University, St. Petersburg, 199034 Russia.
  • Yemelyanov VV; Biology Faculty, St. Petersburg State University, St. Petersburg, 199034 Russia.
  • Lutova LA; Biology Faculty, St. Petersburg State University, St. Petersburg, 199034 Russia.
Appl Biochem Microbiol ; 52(2): 121-137, 2016.
Article en En | MEDLINE | ID: mdl-32214409
Cytokines are a family of signaling polypeptides involved in intercellular interactions in the process of the immune response, as well as in the regulation of a number of normal physiological functions. Cytokines are used in medicine for the treatment of cancer, immune disorders, viral infections, and other socially significant diseases, but the extent of their use is limited by the high production cost of the active agent. The development of this area of pharmacology is associated with the success of genetic engineering, which allows the production of significant amounts of protein by transgenic organisms. The review discusses the latest advances in the production of various cytokines with the use of genetically modified plants.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Appl Biochem Microbiol Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Appl Biochem Microbiol Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos