Interplay between RNA-binding protein HuR and Nox4 as a novel therapeutic target in diabetic kidney disease.

Shi, Qian; Lee, Doug-Yoon; Féliers, Denis; Abboud, Hanna E; Bhat, Manzoor A; Gorin, Yves

Shi, Qian; Lee, Doug-Yoon; Féliers, Denis; Abboud, Hanna E; Bhat, Manzoor A; Gorin, Yves.

Afiliación

Shi Q; Department of Cellular and Integrative Physiology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA. Electronic address: shiq@uthscsa.edu.
Lee DY; Department of Medicine/Division of Nephrology, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Féliers D; Department of Medicine/Division of Nephrology, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Abboud HE; Department of Medicine/Division of Nephrology, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Bhat MA; Department of Cellular and Integrative Physiology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Gorin Y; Department of Medicine/Division of Nephrology, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

Mol Metab ; 36: 100968, 2020 06.

Article en En | MEDLINE | ID: mdl-32240965

Asunto(s)

Nefropatías Diabéticas/genética; Proteína 1 Similar a ELAV/metabolismo; NADPH Oxidasa 4/metabolismo; Animales; Células Cultivadas; Diabetes Mellitus/metabolismo; Diabetes Mellitus Experimental/metabolismo; Nefropatías Diabéticas/terapia; Proteína 1 Similar a ELAV/genética; Glucosa/metabolismo; Humanos; Hiperglucemia/metabolismo; Riñón/patología; Masculino; Ratones; Ratones Endogámicos C57BL; NADPH Oxidasa 4/genética; Proteínas de Unión al ARN/metabolismo; Especies Reactivas de Oxígeno/metabolismo; Transducción de Señal/efectos de los fármacos

Palabras clave

Diabetic nephropathy; Human antigen R protein; NADPH oxidase 4; Translational regulation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nefropatías Diabéticas / Proteína 1 Similar a ELAV / NADPH Oxidasa 4 Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Mol Metab Año: 2020 Tipo del documento: Article Pais de publicación: Alemania

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