[CLINICAL CASE: THE SIDE EFFECTS OF STATINS].

Kukes, V; Chebyshev, N; Pavlova, L; Berechikidze, I; Degtyarevskaya, T; Badriddinova, L

Kukes, V; Chebyshev, N; Pavlova, L; Berechikidze, I; Degtyarevskaya, T; Badriddinova, L.

Afiliación

Kukes V; Sechenov First Moscow State Medical University, Russia.
Chebyshev N; Sechenov First Moscow State Medical University, Russia.
Pavlova L; Sechenov First Moscow State Medical University, Russia.
Berechikidze I; Sechenov First Moscow State Medical University, Russia.
Degtyarevskaya T; Sechenov First Moscow State Medical University, Russia.
Badriddinova L; Sechenov First Moscow State Medical University, Russia.

Georgian Med News ; (299): 75-78, 2020 Feb.

Article en Ru | MEDLINE | ID: mdl-32242849

RESUMEN

The clinical studies, conducted in recent years, suggest that statins increase the activity of telomerase and by that decelerate speed of telomerase shortening. Thus, on one hand, it reduces a risk of cardiovascular diseases development, decelerate aging, but on the other hand, increasing the activity of telomerase, lead to expression rising of gene hTERT, that can make prerequisites for malignancy. That's why, it's necessary to study the subject and develop reliable criteria for safety use of activators-telomerase.

Asunto(s)

Inhibidores de Hidroximetilglutaril-CoA Reductasas/efectos adversos; Telomerasa/metabolismo; Telómero/efectos de los fármacos; Humanos; Inhibidores de Hidroximetilglutaril-CoA Reductasas/uso terapéutico; Telomerasa/genética; Telómero/metabolismo; Acortamiento del Telómero/efectos de los fármacos

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Telómero / Telomerasa / Inhibidores de Hidroximetilglutaril-CoA Reductasas Límite: Humans Idioma: Ru Revista: Georgian Med News Asunto de la revista: MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Georgia

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links