Statins as anti-inflammatory agents: A potential therapeutic role in sight-threatening non-infectious uveitis.
Porto Biomed J
; 2(2): 33-39, 2017.
Article
en En
| MEDLINE
| ID: mdl-32258583
ABSTRACT
In addition to the known lipid-lowering effects, statins are now widely accepted to have anti-inflammatory and immunomodulatory effects. Adjunctive use of statins has proven beneficial in the context of a wide range of inflammatory diseases, including rheumatoid arthritis. Evidence also suggests that statins may also have utility in the management of uveitis, a form of sight threatening inflammation which occurs in the eye. In this article, we outline our rationale behind a clinical trial of simvastatin as a steroid-sparing agent in uveitis, to which patient recruitment started last year. Potential risks associated with the clinical use of statins, including putative effects on the eyes, are discussed.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Porto Biomed J
Año:
2017
Tipo del documento:
Article
País de afiliación:
Reino Unido