Challenges in diagnosis and management of neutropenia upon exposure to immune-checkpoint inhibitors: meta-analysis of a rare immune-related adverse side effect.

Boegeholz, J; Brueggen, C S; Pauli, C; Dimitriou, F; Haralambieva, E; Dummer, R; Manz, M G; Widmer, C C

Boegeholz, J; Brueggen, C S; Pauli, C; Dimitriou, F; Haralambieva, E; Dummer, R; Manz, M G; Widmer, C C.

Afiliación

Boegeholz J; Department of Medical Oncology and Hematology, University and University Hospital Zurich, Zurich, Switzerland.
Brueggen CS; Department of Dermatology, University and University Hospital Zurich, Zurich, Switzerland.
Pauli C; Department of Dermatology, University and University Hospital Zurich, Zurich, Switzerland.
Dimitriou F; Department of Dermatology, University and University Hospital Zurich, Zurich, Switzerland.
Haralambieva E; Institute of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.
Dummer R; Department of Dermatology, University and University Hospital Zurich, Zurich, Switzerland.
Manz MG; Department of Medical Oncology and Hematology, University and University Hospital Zurich, Zurich, Switzerland.
Widmer CC; Department of Medical Oncology and Hematology, University and University Hospital Zurich, Zurich, Switzerland. corinne.widmer@usz.ch.

BMC Cancer ; 20(1): 300, 2020 Apr 14.

Article en En | MEDLINE | ID: mdl-32290812

Asunto(s)

Inhibidores de Puntos de Control Inmunológico/efectos adversos; Melanoma/tratamiento farmacológico; Neutropenia/diagnóstico; Adulto; Anciano; Anciano de 80 o más Años; Antígeno CTLA-4/antagonistas & inhibidores; Dipirona/efectos adversos; Dipirona/uso terapéutico; Femenino; Humanos; Inhibidores de Puntos de Control Inmunológico/uso terapéutico; Inmunoterapia/efectos adversos; Masculino; Melanoma/metabolismo; Melanoma/terapia; Persona de Mediana Edad; Neutropenia/inducido químicamente; Neutropenia/terapia; Receptor de Muerte Celular Programada 1/antagonistas & inhibidores

Palabras clave

Hematological side effects; Immune-checkpoints-inhibitor; Immune-related adverse events; Metamizole; Neutropenia

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de Puntos de Control Inmunológico / Melanoma / Neutropenia Tipo de estudio: Diagnostic_studies / Screening_studies / Systematic_reviews Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: BMC Cancer Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido

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