Airway Epithelial Dynamics in Allergy and Related Chronic Inflammatory Airway Diseases.

Laulajainen-Hongisto, Anu; Toppila-Salmi, Sanna Katriina; Luukkainen, Annika; Kern, Robert

Laulajainen-Hongisto, Anu; Toppila-Salmi, Sanna Katriina; Luukkainen, Annika; Kern, Robert.

Afiliación

Laulajainen-Hongisto A; Department of Otorhinolaryngology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Toppila-Salmi SK; Laboratory of Cellular and Molecular Immunology, Institute of Microbiology of the Czech Academy of Sciences, Prague, Czechia.
Luukkainen A; Haartman Institute, Medicum, University of Helsinki, Helsinki, Finland.
Kern R; Skin and Allergy Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Front Cell Dev Biol ; 8: 204, 2020.

Article en En | MEDLINE | ID: mdl-32292784

ABSTRACT

ABSTRACT

Allergic rhinitis, chronic rhinosinusitis, and asthma are highly prevalent, multifactorial chronic airway diseases. Several environmental and genetic factors affect airway epithelial dynamics leading to activation of inflammatory mechanisms in the airways. This review links environmental factors to host epithelial immunity in airway diseases. Understanding altered homeostasis of the airway epithelium might provide important targets for diagnostics and therapy of chronic airway diseases.

Palabras clave

allergic rhinitis (AR); asthma; chronic rhinosinusitis; epithelium; inflammation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Cell Dev Biol Año: 2020 Tipo del documento: Article País de afiliación: Finlandia

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