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CXCL10 and CCL21 Promote Migration of Pancreatic Cancer Cells Toward Sensory Neurons and Neural Remodeling in Tumors in Mice, Associated With Pain in Patients.
Hirth, Michael; Gandla, Jagadeesh; Höper, Christiane; Gaida, Matthias M; Agarwal, Nitin; Simonetti, Manuela; Demir, Aykut; Xie, Yong; Weiss, Cleo; Michalski, Christoph W; Hackert, Thilo; Ebert, Matthias P; Kuner, Rohini.
Afiliación
  • Hirth M; Institute of Pharmacology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany; Department of Medicine II, University Medical Center Mannheim, Medical Faculty at Mannheim, University of Heidelberg, Mannheim, Germany.
  • Gandla J; Institute of Pharmacology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.
  • Höper C; Institute of Pharmacology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.
  • Gaida MM; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany; Institute of Pathology, University Hospital Johannes Gutenberg-University Mainz, Mainz, Germany.
  • Agarwal N; Institute of Pharmacology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.
  • Simonetti M; Institute of Pharmacology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.
  • Demir A; Institute of Pharmacology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.
  • Xie Y; Institute of Pharmacology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.
  • Weiss C; Institute of Pathology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
  • Michalski CW; Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany; Department of Surgery, Halle University Hospital, Halle, Germany.
  • Hackert T; Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.
  • Ebert MP; Department of Medicine II, University Medical Center Mannheim, Medical Faculty at Mannheim, University of Heidelberg, Mannheim, Germany.
  • Kuner R; Institute of Pharmacology, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. Electronic address: rohini.kuner@pharma.uni-heidelberg.de.
Gastroenterology ; 159(2): 665-681.e13, 2020 08.
Article en En | MEDLINE | ID: mdl-32330476
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Células Receptoras Sensoriales / Movimiento Celular / Carcinoma Ductal Pancreático / Quimiocina CCL21 / Quimiocina CXCL10 / Dolor en Cáncer / Ganglios Espinales Tipo de estudio: Clinical_trials / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Gastroenterology Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Células Receptoras Sensoriales / Movimiento Celular / Carcinoma Ductal Pancreático / Quimiocina CCL21 / Quimiocina CXCL10 / Dolor en Cáncer / Ganglios Espinales Tipo de estudio: Clinical_trials / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Gastroenterology Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos