Gold Nanoparticle Based Electrochemical Immunosensor for Detection of T3 Hormone.
J Nanosci Nanotechnol
; 20(10): 6057-6062, 2020 10 01.
Article
en En
| MEDLINE
| ID: mdl-32384952
ABSTRACT
We report a nanoparticles based electrochemical immunosensor to detect and quantify triiodothyronine (T3) hormone. Immunosensor developed using gold nanoparticles and anti-T3 antibody, was employed for quantification of T3 antigen using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) technique. The electrochemical response of the developed immunosensor correlates well with the amount of antigen present in the sample. With increase in antigen concentration the immunocomplex formation on electrode surface increases and hence redox current decreases. The immunosensor shows a lower limit of detection of 1 pg/mL and dynamic range from 1 to 500 pg/mL. Sensitivity of the immunosensor was found to be 29.81 µA/pg/mL/cm².
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Técnicas Biosensibles
/
Nanopartículas del Metal
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
J Nanosci Nanotechnol
Año:
2020
Tipo del documento:
Article
País de afiliación:
India