Prediction of clinical diagnosis of Alzheimer's disease, vascular, mixed, and all-cause dementia by a polygenic risk score and APOE status in a community-based cohort prospectively followed over 17 years.

Stocker, H; Perna, L; Weigl, K; Möllers, T; Schöttker, B; Thomsen, H; Holleczek, B; Rujescu, D; Brenner, H

Prediction of clinical diagnosis of Alzheimer's disease, vascular, mixed, and all-cause dementia by a polygenic risk score and APOE status in a community-based cohort prospectively followed over 17 years.

Stocker, H; Perna, L; Weigl, K; Möllers, T; Schöttker, B; Thomsen, H; Holleczek, B; Rujescu, D; Brenner, H.

Afiliación

Stocker H; Network Aging Research, Heidelberg University, Heidelberg, Germany. h.stocker@dkfz-heidelberg.de.
Perna L; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany. h.stocker@dkfz-heidelberg.de.
Weigl K; Medical Faculty, Heidelberg University, Heidelberg, Germany. h.stocker@dkfz-heidelberg.de.
Möllers T; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.
Schöttker B; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
Thomsen H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.
Holleczek B; Network Aging Research, Heidelberg University, Heidelberg, Germany.
Rujescu D; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.
Brenner H; Medical Faculty, Heidelberg University, Heidelberg, Germany.

Mol Psychiatry ; 26(10): 5812-5822, 2021 10.

Article en En | MEDLINE | ID: mdl-32404947

Asunto(s)

Enfermedad de Alzheimer; Enfermedad de Alzheimer/diagnóstico; Enfermedad de Alzheimer/genética; Apolipoproteína E4/genética; Apolipoproteínas E/genética; Estudio de Asociación del Genoma Completo; Genotipo; Humanos; Estudios Prospectivos; Factores de Riesgo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Alzheimer Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido

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