Probiotics and the Microbiota-Gut-Brain Axis: Focus on Psychiatry.
Curr Nutr Rep
; 9(3): 171-182, 2020 09.
Article
en En
| MEDLINE
| ID: mdl-32406013
PURPOSE OF REVIEW: Probiotics are living bacteria, which when ingested in adequate amounts, confer health benefits. Gut microbes are suggested to play a role in many psychiatric disorders and could be a potential therapeutic target. Between the gut and the brain, there is a bi-directional communication pathway called the microbiota-gut-brain axis. The purpose of this review is to examine data from recent interventional studies focusing on probiotics and the gut-brain axis for the treatment of depression, anxiety and schizophrenia. RECENT FINDINGS: Probiotics are likely to improve depression but not schizophrenia. Regarding anxiety, there is only one trial which showed an effect of a multispecies probiotic. However, determinants like the duration of treatment, dosage and interactions have not been thoroughly investigated and deserve more scientific attention. Microbiome-based therapies such as probiotics could be cautiously recommended for depression to enhance beneficial bacteria in the gut and to improve mood through the gut-brain axis.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Probióticos
/
Microbioma Gastrointestinal
/
Trastornos Mentales
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Nutr Rep
Año:
2020
Tipo del documento:
Article
País de afiliación:
Irlanda
Pais de publicación:
Estados Unidos