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Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures.
Vander Velde, Robert; Yoon, Nara; Marusyk, Viktoriya; Durmaz, Arda; Dhawan, Andrew; Miroshnychenko, Daria; Lozano-Peral, Diego; Desai, Bina; Balynska, Olena; Poleszhuk, Jan; Kenian, Liu; Teng, Mingxiang; Abazeed, Mohamed; Mian, Omar; Tan, Aik Choon; Haura, Eric; Scott, Jacob; Marusyk, Andriy.
Afiliación
  • Vander Velde R; Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
  • Yoon N; Department of Molecular Medicine, University of South Florida, Tampa, FL, USA.
  • Marusyk V; Department of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, OH, USA.
  • Durmaz A; Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
  • Dhawan A; Department of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, OH, USA.
  • Miroshnychenko D; Systems Biology and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
  • Lozano-Peral D; Department of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, OH, USA.
  • Desai B; Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
  • Balynska O; Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
  • Poleszhuk J; Supercomputer and Bioinnovation Center, University of Málaga, Málaga, Spain.
  • Kenian L; Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
  • Teng M; University of South Florida Cancer Biology PhD Program, Tampa, FL, USA.
  • Abazeed M; Department of Cancer Physiology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
  • Mian O; Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland.
  • Tan AC; Department of Pathology, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
  • Haura E; Department of Biostatistic and Bioinformatics, H Lee Moffitt Cancer Centre and Research Institute, Tampa, FL, USA.
  • Scott J; Department of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, OH, USA.
  • Marusyk A; Department of Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, OH, USA.
Nat Commun ; 11(1): 2393, 2020 05 14.
Article en En | MEDLINE | ID: mdl-32409712

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Quinasa de Linfoma Anaplásico / Neoplasias Pulmonares / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Resistencia a Antineoplásicos / Quinasa de Linfoma Anaplásico / Neoplasias Pulmonares / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos