Costus pictus D. Don leaf extract stimulates GLP-1 secretion from GLUTag L-cells and has cytoprotective effects in BRIN-BD11 ß-cells.

Patibandla, Chinmai; Khan, Zahidul Islam; MacGregor, Louise; Campbell, Mark James; Patterson, Steven

Patibandla, Chinmai; Khan, Zahidul Islam; MacGregor, Louise; Campbell, Mark James; Patterson, Steven.

Afiliación

Patibandla C; Department of Biological and Biomedical Sciences, School of Health and Life Sciences, Glasgow Caledonian University, Cowcaddens Road, Glasgow, G4 0BA, UK. Electronic address: cpatib10@gcu.ac.uk.
Khan ZI; Department of Biological and Biomedical Sciences, School of Health and Life Sciences, Glasgow Caledonian University, Cowcaddens Road, Glasgow, G4 0BA, UK. Electronic address: zahidul.khan@gcu.ac.uk.
MacGregor L; Department of Biological and Biomedical Sciences, School of Health and Life Sciences, Glasgow Caledonian University, Cowcaddens Road, Glasgow, G4 0BA, UK. Electronic address: louisemacgregor16@hotmail.co.uk.
Campbell MJ; Department of Biological and Biomedical Sciences, School of Health and Life Sciences, Glasgow Caledonian University, Cowcaddens Road, Glasgow, G4 0BA, UK. Electronic address: mcampbell95@hotmail.co.uk.
Patterson S; Department of Biological and Biomedical Sciences, School of Health and Life Sciences, Glasgow Caledonian University, Cowcaddens Road, Glasgow, G4 0BA, UK. Electronic address: Steven.Patterson@gcu.ac.uk.

J Ethnopharmacol ; 260: 112970, 2020 Oct 05.

Article en En | MEDLINE | ID: mdl-32422353

Asunto(s)

Costus; Células Enteroendocrinas/efectos de los fármacos; Péptido 1 Similar al Glucagón/metabolismo; Hipoglucemiantes/farmacología; Células Secretoras de Insulina/efectos de los fármacos; Extractos Vegetales/farmacología; Hojas de la Planta; Animales; Línea Celular; Costus/química; Citocinas/toxicidad; Células Enteroendocrinas/metabolismo; Glucosa/toxicidad; Hipoglucemiantes/aislamiento & purificación; Insulina/metabolismo; Células Secretoras de Insulina/metabolismo; Células Secretoras de Insulina/patología; Ratones; Palmitatos/toxicidad; Extractos Vegetales/aislamiento & purificación; Hojas de la Planta/química; Ratas; Vías Secretoras

Palabras clave

Costus pictus; Cytoprotection; GLP-1; L-cell; ß-Cell

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Extractos Vegetales / Hojas de la Planta / Células Enteroendocrinas / Costus / Células Secretoras de Insulina / Péptido 1 Similar al Glucagón / Hipoglucemiantes Límite: Animals Idioma: En Revista: J Ethnopharmacol Año: 2020 Tipo del documento: Article

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