Cardiovascular Consequences of Skeletal Muscle Impairments in Breast Cancer.
Sports (Basel)
; 8(6)2020 May 31.
Article
en En
| MEDLINE
| ID: mdl-32486406
ABSTRACT
Breast cancer survivors suffer from disproportionate cardiovascular disease risk compared to age-matched controls. Beyond direct cardiotoxic effects due to treatments such as chemotherapy and radiation, breast-cancer-related reductions in skeletal muscle mass, quality and oxidative capacity may further contribute to cardiovascular disease risk in this population by limiting the ability to engage in aerobic exercise-a known promoter of cardiovascular health. Indeed, 20%-30% decreases in peak oxygen consumption are commonly observed in breast cancer survivors, which are indicative of exercise intolerance. Thus, breast-cancer-related skeletal muscle damage may reduce exercise-based opportunities for cardiovascular disease risk reduction. Resistance training is a potential strategy to improve skeletal muscle health in this population, which in turn may enhance the capacity to engage in aerobic exercise and reduce cardiovascular disease risk.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Sports (Basel)
Año:
2020
Tipo del documento:
Article
País de afiliación:
Estados Unidos