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Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI.
Kreimer, Aimée R; Chaturvedi, Anil K; Alemany, Laia; Anantharaman, Devasena; Bray, Freddie; Carrington, Mary; Doorbar, John; D'Souza, Gypsyamber; Fakhry, Carole; Ferris, Robert L; Gillison, Maura; Neil Hayes, D; Hildesheim, Allan; Huang, Shao Hui; Kowalski, Luiz P; Lang Kuhs, Krystle A; Lewis, James; Lowy, Douglas R; Mehanna, Hisham; Ness, Andy; Pawlita, Michael; Pinheiro, Maisa; Schiller, John; Shiels, Meredith S; Tota, Joseph; Mirabello, Lisa; Warnakulasuriya, Saman; Waterboer, Tim; Westra, William; Chanock, Stephen; Brennan, Paul.
Afiliación
  • Kreimer AR; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: kreimera@mail.nih.gov.
  • Chaturvedi AK; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: chaturva@mail.nih.gov.
  • Alemany L; Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; Epidemiology and Public Health, Centro de Investigación Biomédica en Red: Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain. Electronic address: lalemany@iconcologia.net.
  • Anantharaman D; Rajiv Gandhi Centre for Biotechnology, Trivandrum, India. Electronic address: devasena@rgcb.res.in.
  • Bray F; International Agency for Research on Cancer, Lyon, France. Electronic address: Brayf@iarc.fr.
  • Carrington M; Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States. Electronic address: carringm@mail.nih.gov.
  • Doorbar J; University of Cambridge, Cambridge, United Kingdom. Electronic address: jd121@cam.ac.uk.
  • D'Souza G; Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States. Electronic address: Gdsouza2@jhu.edu.
  • Fakhry C; Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, United States. Electronic address: cfakhry@jhmi.edu.
  • Ferris RL; UPMC Hillman Cancer Center, Pittsburgh, PA, United States. Electronic address: ferrrl@upmc.edu.
  • Gillison M; The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address: mgillison@mdanderson.org.
  • Neil Hayes D; The University of Tennessee Health Science Center, Memphis, TN, United States. Electronic address: Neil.Hayes@uthsc.edu.
  • Hildesheim A; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: hildesha@exchange.nih.gov.
  • Huang SH; University of Toronto, Princess Margaret Hospital, Toronto, Ontario, Canada. Electronic address: ShaoHui.Huang@rmp.uhn.ca.
  • Kowalski LP; A.C. Camargo Cancer Center, São Paulo, Brazil. Electronic address: lp_kowalski@uol.com.br.
  • Lang Kuhs KA; Vanderbilt University Medical Center, Nashville, TN, United States. Electronic address: krystle.kuhs@vumc.org.
  • Lewis J; Vanderbilt University Medical Center, Nashville, TN, United States. Electronic address: james.lewis@vanderbilt.edu.
  • Lowy DR; Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States; Office of the Director, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: lowyd@mail.nih.gov.
  • Mehanna H; Institute for Head and Neck Studies and Education, University of Birmingham, Birmingham, United Kingdom. Electronic address: h.mehanna@bham.ac.uk.
  • Ness A; NIHR Bristol Biomedical Research Centre, University of Bristol NHS Foundation Trust and University of Bristol, Bristol, United Kingdom. Electronic address: Andy.Ness@bristol.ac.uk.
  • Pawlita M; German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: m.pawlita@dkfz-heidelberg.de.
  • Pinheiro M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: maisa.pinheiro@nih.gov.
  • Schiller J; Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: schillej@dc37a.nci.nih.gov.
  • Shiels MS; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: shielsms@mail.nih.gov.
  • Tota J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: joseph.tota@nih.gov.
  • Mirabello L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: mirabellol@mail.nih.gov.
  • Warnakulasuriya S; King's College London, London, United Kingdom; WHO Collaborating Centre for Oral Cancer, United Kingdom. Electronic address: saman.warne@kcl.ac.uk.
  • Waterboer T; German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: T.Waterboer@dkfz-heidelberg.de.
  • Westra W; Icahn School of Medicine at Mount Sinai, New York, NY, United States. Electronic address: william.westra@mountsinai.org.
  • Chanock S; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: hanocks@mail.nih.gov.
  • Brennan P; International Agency for Research on Cancer, Lyon, France. Electronic address: gep@iarc.fr.
Oral Oncol ; 108: 104736, 2020 09.
Article en En | MEDLINE | ID: mdl-32502860
ABSTRACT
Cancer of the oropharynx has attracted considerable attention in recent years given (1) an increasing incidence in selected populations over the past three decades; (2) the discovery of human papillomavirus (HPV) infection as the driver of the increase, as opposed to the traditional risk factors such as tobacco (smoking and chewing) and alcohol; and (3) the promise of new prevention and treatment strategies. As a result of such developments, the International Agency for Research on Cancer (IARC) and the US National Cancer Institute (NCI), convened the fourth Cancer Seminar meeting in November 2018 to focus on this topic. This report summarizes the proceedings a review of recent science on the descriptive epidemiology, etiology, biology, genetics, early detection, pathology and treatment of HPV-positive oropharyngeal cancer, and the formulation of key research questions to be addressed.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Papillomaviridae / Neoplasias Orofaríngeas / Infecciones por Papillomavirus Tipo de estudio: Risk_factors_studies / Screening_studies Límite: Aged / Humans / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Oral Oncol Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Papillomaviridae / Neoplasias Orofaríngeas / Infecciones por Papillomavirus Tipo de estudio: Risk_factors_studies / Screening_studies Límite: Aged / Humans / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Oral Oncol Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article