Role of Interleukin-6 in Lung Complications in Patients With COVID-19: Therapeutic Implications.
In Vivo
; 34(3 Suppl): 1589-1592, 2020 Jun.
Article
en En
| MEDLINE
| ID: mdl-32503815
ABSTRACT
COVID-19 is viral respiratory infection with frequently fatal lung complications in the elderly or in people with serious comorbidities. Lung destruction appears to be associated with a cytokine storm related to an increased level of interleukin-6 (IL6). Therapeutic targeting of the interleukin-6 signaling pathway can attenuate such a cytokine storm and can be beneficial for patients with COVID-19 in danger of pulmonary failure. This article demonstrates the importance of IL6 in progression of disease and the possibility of inhibition of IL6 signaling in COVID-19 therapy.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neumonía Viral
/
Interleucina-6
/
Infecciones por Coronavirus
/
Síndrome de Liberación de Citoquinas
Límite:
Humans
Idioma:
En
Revista:
In Vivo
Asunto de la revista:
NEOPLASIAS
Año:
2020
Tipo del documento:
Article