Hair Cell Transduction Efficiency of Single- and Dual-AAV Serotypes in Adult Murine Cochleae.

Omichi, Ryotaro; Yoshimura, Hidekane; Shibata, Seiji B; Vandenberghe, Luk H; Smith, Richard J H

Omichi, Ryotaro; Yoshimura, Hidekane; Shibata, Seiji B; Vandenberghe, Luk H; Smith, Richard J H.

Afiliación

Omichi R; Molecular Otolaryngology and Renal Research Laboratories, Carver College of Medicine, University of Iowa, 285 Newton Road, 5270 CBRB, Iowa City, IA 52242, USA.
Yoshimura H; Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-Cho, Kita-Ku, Okayama 700-8558, Japan.
Shibata SB; Molecular Otolaryngology and Renal Research Laboratories, Carver College of Medicine, University of Iowa, 285 Newton Road, 5270 CBRB, Iowa City, IA 52242, USA.
Vandenberghe LH; Department of Otorhinolaryngology, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
Smith RJH; Molecular Otolaryngology and Renal Research Laboratories, Carver College of Medicine, University of Iowa, 285 Newton Road, 5270 CBRB, Iowa City, IA 52242, USA.

Mol Ther Methods Clin Dev ; 17: 1167-1177, 2020 Jun 12.

Article en En | MEDLINE | ID: mdl-32518805

Palabras clave

AAV2; adeno-associated virus; deafness; dual vectors; gene therapy; hair cells; hearing loss; injection; tropism; viral vectors

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Mol Ther Methods Clin Dev Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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