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Supramolecular subphthalocyanine complexes-cellular uptake and phototoxicity.
Dubbert, Justin; Höing, Alexander; Riek, Nathalie; Knauer, Shirley K; Voskuhl, Jens.
Afiliación
  • Dubbert J; Institute of Organic Chemistry, University of Duisburg-Essen, Universitätsstrasse 7, 45117, Essen, Germany. jens.voskuhl@uni-due.de.
  • Höing A; Department of Molecular Biology II, Center of Medical Biotechnology (ZMB), University of Duisburg-Essen, Universitätsstrasse 5, D-45117 Essen, Germany.
  • Riek N; Institute of Organic Chemistry, University of Duisburg-Essen, Universitätsstrasse 7, 45117, Essen, Germany. jens.voskuhl@uni-due.de.
  • Knauer SK; Department of Molecular Biology II, Center of Medical Biotechnology (ZMB), University of Duisburg-Essen, Universitätsstrasse 5, D-45117 Essen, Germany.
  • Voskuhl J; Institute of Organic Chemistry, University of Duisburg-Essen, Universitätsstrasse 7, 45117, Essen, Germany. jens.voskuhl@uni-due.de.
Chem Commun (Camb) ; 56(55): 7653-7656, 2020 Jul 09.
Article en En | MEDLINE | ID: mdl-32520022
In this communication we report on the synthesis and application of axially functionalized boron-subphthalocyanines (SubPC) which are able to form host-guest complexes with cyclodextrins. Here, a tert-butylphenyl substituted SubPC was investigated concerning its complexation with ß-cyclodextrin (ß-CD) and a ß-cyclodextrin polymer. NMR-titrations showed the formation of a 1 : 1 complex with ß-CD. These assemblies were analyzed for their cellular distribution as well as their phototoxicity towards HeLa cells.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fármacos Fotosensibilizantes / Indoles Límite: Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fármacos Fotosensibilizantes / Indoles Límite: Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido