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A lipidome atlas in MS-DIAL 4.
Tsugawa, Hiroshi; Ikeda, Kazutaka; Takahashi, Mikiko; Satoh, Aya; Mori, Yoshifumi; Uchino, Haruki; Okahashi, Nobuyuki; Yamada, Yutaka; Tada, Ipputa; Bonini, Paolo; Higashi, Yasuhiro; Okazaki, Yozo; Zhou, Zhiwei; Zhu, Zheng-Jiang; Koelmel, Jeremy; Cajka, Tomas; Fiehn, Oliver; Saito, Kazuki; Arita, Masanori; Arita, Makoto.
Afiliación
  • Tsugawa H; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. hiroshi.tsugawa@riken.jp.
  • Ikeda K; RIKEN Center for Sustainable Resource Science, Yokohama, Japan. hiroshi.tsugawa@riken.jp.
  • Takahashi M; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Satoh A; Department of Applied Genomics, Kazusa DNA Research Institute, Chiba, Japan.
  • Mori Y; RIKEN Center for Sustainable Resource Science, Yokohama, Japan.
  • Uchino H; RIKEN Center for Sustainable Resource Science, Yokohama, Japan.
  • Okahashi N; Bruker, Yokohama, Japan.
  • Yamada Y; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Tada I; Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.
  • Bonini P; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
  • Higashi Y; Graduate School of Information Science and Technology, Osaka University, Osaka, Japan.
  • Okazaki Y; RIKEN Center for Sustainable Resource Science, Yokohama, Japan.
  • Zhou Z; Department of Genetics, The Graduate University for Advanced Studies, SOKENDAI, Miura, Japan.
  • Zhu ZJ; NGAlab, Tarragona, Spain.
  • Koelmel J; RIKEN Center for Sustainable Resource Science, Yokohama, Japan.
  • Cajka T; RIKEN Center for Sustainable Resource Science, Yokohama, Japan.
  • Fiehn O; Graduate School of Bioresources, Mie University, Tsu, Japan.
  • Saito K; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
  • Arita M; University of Chinese Academy of Sciences, Beijing, China.
  • Arita M; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.
Nat Biotechnol ; 38(10): 1159-1163, 2020 10.
Article en En | MEDLINE | ID: mdl-32541957
We present Mass Spectrometry-Data Independent Analysis software version 4 (MS-DIAL 4), a comprehensive lipidome atlas with retention time, collision cross-section and tandem mass spectrometry information. We formulated mass spectral fragmentations of lipids across 117 lipid subclasses and included ion mobility tandem mass spectrometry. Using human, murine, algal and plant biological samples, we annotated and semiquantified 8,051 lipids using MS-DIAL 4 with a 1-2% estimated false discovery rate. MS-DIAL 4 helps standardize lipidomics data and discover lipid pathways.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Análisis de Datos / Lipidómica / Lípidos Idioma: En Revista: Nat Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Análisis de Datos / Lipidómica / Lípidos Idioma: En Revista: Nat Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos