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SphK2 confers 5-fluorouracil resistance to colorectal cancer via upregulating H3K56ac-mediated DPD expression.
Zhang, Yu-Hang; Shi, Wen-Na; Wu, Shu-Hua; Miao, Rong-Rong; Sun, Shi-Yue; Luo, Dong-Dong; Wan, Sheng-Biao; Guo, Zhi-Kun; Wang, Wen-Yu; Yu, Xin-Feng; Cui, Shu-Xiang; Qu, Xian-Jun.
Afiliación
  • Zhang YH; Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
  • Shi WN; Department of Pharmacy, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
  • Wu SH; Department of Pathology, Hospital of Binzhou Medical University, Shandong, China.
  • Miao RR; Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
  • Sun SY; Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
  • Luo DD; Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
  • Wan SB; Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
  • Guo ZK; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, China.
  • Wang WY; Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
  • Yu XF; Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
  • Cui SX; Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, China. sxccui@ccmu.edu.cn.
  • Qu XJ; Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, China. qxj@ccmu.edu.cn.
Oncogene ; 39(29): 5214-5227, 2020 07.
Article en En | MEDLINE | ID: mdl-32546724
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Fosfotransferasas (Aceptor de Grupo Alcohol) / Resistencia a Antineoplásicos / Dihidrouracilo Deshidrogenasa (NADP) / Fluorouracilo Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Fosfotransferasas (Aceptor de Grupo Alcohol) / Resistencia a Antineoplásicos / Dihidrouracilo Deshidrogenasa (NADP) / Fluorouracilo Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido