Microvascular disease confers additional risk to COVID-19 infection.
Med Hypotheses
; 144: 109999, 2020 Nov.
Article
en En
| MEDLINE
| ID: mdl-32570168
The majority of fatalities thus far in the COVID-19 pandemic have been attributed to pneumonia. As expected, the fatality rate reported in China is higher in people with chronic pulmonary disease (6.3%) and those who have cancer (5.6%). According to the American College of Cardiology Clinical Bulletin "COVID-19 Clinical Guidance for the CV Care Team", there is a significantly higher fatality rate in people who are elderly (8.0% 70-79 years; 14.8% ≥80 years), diabetic (7.3%), hypertensive (6.0%), or have known cardiovascular disease (CVD) (10.5%). We propose a biological reason for the higher mortality risk in these populations that is apparent. We further present a set of pathophysiological reasons for the heightened danger that could lead to therapies for enhanced management and prevention.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pandemias
/
COVID-19
/
Inmunidad Innata
Tipo de estudio:
Etiology_studies
/
Guideline
Límite:
Adult
/
Child
/
Humans
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Med Hypotheses
Año:
2020
Tipo del documento:
Article
Pais de publicación:
Estados Unidos