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EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development.
Rej, Rohan Kalyan; Wang, Changwei; Lu, Jianfeng; Wang, Mi; Petrunak, Elyse; Zawacki, Kaitlin P; McEachern, Donna; Fernandez-Salas, Ester; Yang, Chao-Yie; Wang, Lu; Li, Ruiting; Chinnaswamy, Krishnapriya; Wen, Bo; Sun, Duxin; Stuckey, Jeanne; Zhou, Yunlong; Chen, Jianyong; Tang, Guozhi; Wang, Shaomeng.
Afiliación
  • Rej RK; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Wang C; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Lu J; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Wang M; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Petrunak E; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Zawacki KP; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • McEachern D; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Fernandez-Salas E; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Yang CY; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Wang L; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Li R; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Chinnaswamy K; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Wen B; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Sun D; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Stuckey J; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Zhou Y; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Chen J; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Tang G; Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Wang S; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
J Med Chem ; 63(13): 7252-7267, 2020 07 09.
Article en En | MEDLINE | ID: mdl-32580550
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bibliotecas de Moléculas Pequeñas / Complejo Represivo Polycomb 2 / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bibliotecas de Moléculas Pequeñas / Complejo Represivo Polycomb 2 / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos