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Age-Induced Reduction in Human Lipolysis: A Potential Role for Adipocyte Noradrenaline Degradation.
Gao, Hui; Arner, Peter; Beauchef, Gallic; Guéré, Christelle; Vie, Katell; Dahlman, Ingrid; Mejhert, Niklas; Rydén, Mikael.
Afiliación
  • Gao H; Department of Biosciences and Nutrition (H2), Karolinska Institutet, Huddinge 141 83, Sweden.
  • Arner P; Department of Medicine (H7), Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden.
  • Beauchef G; CLARINS Laboratoires, 95300 Pontoise, France.
  • Guéré C; CLARINS Laboratoires, 95300 Pontoise, France.
  • Vie K; CLARINS Laboratoires, 95300 Pontoise, France.
  • Dahlman I; Department of Medicine (H7), Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden.
  • Mejhert N; Department of Medicine (H7), Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden.
  • Rydén M; Department of Medicine (H7), Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden. Electronic address: mikael.ryden@ki.se.
Cell Metab ; 32(1): 1-3, 2020 07 07.
Article en En | MEDLINE | ID: mdl-32589948
ABSTRACT
Gao et al. report that the observed reduction in adipose lipolysis with age in women could be explained by an upregulation of the catecholamine-degradation pathway in subcutaneous adipocytes. However, in contrast to findings in mice, these pathways are enriched in adipocytes and not in immune cells, suggesting species-specific differences in aging mechanisms.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inflamasomas / Lipólisis Límite: Animals / Humans Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2020 Tipo del documento: Article País de afiliación: Suecia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inflamasomas / Lipólisis Límite: Animals / Humans Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2020 Tipo del documento: Article País de afiliación: Suecia