ProT-&#945; gene transfer attenuates cardiopulmonary remedying and mortality in a flow-induced pulmonary hypertension rat model.

Roan, Jun-Neng; Hsu, Chih-Hsin; Fang, Shih-Yuan; Chiu, Meng-Shuan; Wu, Chao-Liang; Shiau, Ai-Li; Lam, Chen-Fuh

ProT-α gene transfer attenuates cardiopulmonary remedying and mortality in a flow-induced pulmonary hypertension rat model.

Roan, Jun-Neng; Hsu, Chih-Hsin; Fang, Shih-Yuan; Chiu, Meng-Shuan; Wu, Chao-Liang; Shiau, Ai-Li; Lam, Chen-Fuh.

Afiliación

Roan JN; Division of Cardiovascular Surgery, Department of Surgery, National Cheng Kung University Hospital; Medical Device Innovation Center, National Cheng Kung University Hospital.
Hsu CH; Division of Cardiology, Department of Internal Medicine.
Fang SY; Department of Anesthesiology, National Cheng Kung University Hospital.
Chiu MS; Department of Anesthesiology, National Cheng Kung University Hospital.
Wu CL; Institute of Basic Medical Science; Department of Biochemistry.
Shiau AL; Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Lam CF; Department of Anesthesiology, E-Da Hospital/I-Shou University, Kaohsiung city, Taiwan. Electronic address: ed110208@edah.org.tw.

J Heart Lung Transplant ; 39(10): 1126-1135, 2020 10.

Article en En | MEDLINE | ID: mdl-32593559

Asunto(s)

Técnicas de Transferencia de Gen; Hipertensión Pulmonar/terapia; Factor de Crecimiento Transformador beta/genética; Animales; Modelos Animales de Enfermedad; Hipertensión Pulmonar/genética; Hipertensión Pulmonar/mortalidad; Masculino; Estrés Oxidativo; Ratas; Ratas Sprague-Dawley; Transducción de Señal; Tasa de Supervivencia/tendencias; Factor de Crecimiento Transformador beta/metabolismo

Palabras clave

flow-induced pulmonary hypertension; microRNA-223; prothymosin α; pulmonary artery; vascular smooth muscle cells

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor de Crecimiento Transformador beta / Técnicas de Transferencia de Gen / Hipertensión Pulmonar Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Heart Lung Transplant Asunto de la revista: CARDIOLOGIA / TRANSPLANTE Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos

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