Reabsorption of bile acids regulated by FXR-OATP1A2 is the main factor for the formation of cholesterol gallstone.

Cai, Jingli; Wang, Zhaowen; Chen, Guiming; Li, Dapeng; Liu, Jun; Hu, Hai; Qin, Jian

Cai, Jingli; Wang, Zhaowen; Chen, Guiming; Li, Dapeng; Liu, Jun; Hu, Hai; Qin, Jian.

Afiliación

Cai J; Center of Gallbladder Disease, Shanghai East Hospital, Institute of Gallstone Disease, Tongji University School of Medicine, Shanghai, China.
Wang Z; Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chen G; Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li D; Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liu J; Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hu H; Center of Gallbladder Disease, Shanghai East Hospital, Institute of Gallstone Disease, Tongji University School of Medicine, Shanghai, China.
Qin J; Department of General Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Am J Physiol Gastrointest Liver Physiol ; 319(3): G303-G308, 2020 09 01.

Article en En | MEDLINE | ID: mdl-32597704

Asunto(s)

Ácidos y Sales Biliares/metabolismo; Colelitiasis/genética; Colesterol/metabolismo; Transportadores de Anión Orgánico/genética; Proteínas de Unión al ARN/genética; Adulto; Colelitiasis/metabolismo; Femenino; Humanos; Masculino; Persona de Mediana Edad; Transportadores de Anión Orgánico/metabolismo; ARN Mensajero/genética; Proteínas de Unión al ARN/metabolismo; Esteroide 12-alfa-Hidroxilasa/genética; Esteroide 12-alfa-Hidroxilasa/metabolismo; Ácido Taurodesoxicólico/metabolismo; Ácido Taurolitocólico/metabolismo

Palabras clave

FXR; OATP; bile acids; gallstone

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácidos y Sales Biliares / Colelitiasis / Colesterol / Proteínas de Unión al ARN / Transportadores de Anión Orgánico Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Physiol Gastrointest Liver Physiol Asunto de la revista: FISIOLOGIA / GASTROENTEROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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