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New BACE1 Chimeric Peptide Inhibitors Selectively Prevent AßPP-ß Cleavage Decreasing Amyloid-ß Production and Accumulation in Alzheimer's Disease Models.
Resende, Rosa; Ferreira-Marques, Marisa; Moreira, Patrícia; Coimbra, Judite R M; Baptista, Salete J; Isidoro, Ciro; Salvador, Jorge A R; Dinis, Teresa C P; Pereira, Cláudia F; Santos, Armanda E.
Afiliación
  • Resende R; University of Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.
  • Ferreira-Marques M; University of Coimbra, Institute for Interdisciplinary Research (IIIUC), Coimbra, Portugal.
  • Moreira P; University of Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.
  • Coimbra JRM; University of Coimbra, Faculty of Pharmacy, Laboratory of Pharmacology, Coimbra, Portugal.
  • Baptista SJ; University of Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.
  • Isidoro C; University of Coimbra, Faculty of Pharmacy, Laboratory of Pharmacology, Coimbra, Portugal.
  • Salvador JAR; University of Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.
  • Dinis TCP; University of Coimbra, Faculty of Pharmacy, Laboratory of Pharmaceutical Chemistry, Coimbra, Portugal.
  • Pereira CF; University of Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), Center for Neuroscience and Cell Biology (CNC), Coimbra, Portugal.
  • Santos AE; Chem4Pharma, Coimbra, Portugal.
J Alzheimers Dis ; 76(4): 1317-1337, 2020.
Article en En | MEDLINE | ID: mdl-32597812
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Péptidos beta-Amiloides / Ácido Aspártico Endopeptidasas / Precursor de Proteína beta-Amiloide / Secretasas de la Proteína Precursora del Amiloide Límite: Animals / Humans Idioma: En Revista: J Alzheimers Dis Asunto de la revista: GERIATRIA / NEUROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Portugal
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Péptidos beta-Amiloides / Ácido Aspártico Endopeptidasas / Precursor de Proteína beta-Amiloide / Secretasas de la Proteína Precursora del Amiloide Límite: Animals / Humans Idioma: En Revista: J Alzheimers Dis Asunto de la revista: GERIATRIA / NEUROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Portugal