Correlation of Chemical Urinalysis to Microscopic Urinalysis and Urine Culture: Implications for Reflex Urinalysis Workflows.
J Appl Lab Med
; 5(4): 724-731, 2020 07 01.
Article
en En
| MEDLINE
| ID: mdl-32603438
ABSTRACT
BACKGROUND:
Urinalysis (UA) reflex testing approaches, which offer potential for savings in labor and result turnaround time, may rely on the performance of a chemical UA screen to determine which urine samples need microscopic UA and/or urine culture. We correlated chemical UA, microscopic UA, and urine culture results to determine the performance of chemical UA as a screening tool for reflex testing approaches.METHODS:
Consecutive UA results for 9127 tests (simultaneous chemical UA and microscopic UA) were retrospectively reviewed and correlated. Urine culture results were also correlated for 3127 samples that had urine culture ordered within 24 h of UA. Positivity criteria for each UA method were predefined.RESULTS:
Chemical UA yielded the following performance specifications for predicting microscopicfindings:
93.0% sensitivity, 56.9% specificity, 64.7% positive predictive value, 90.5% negative predictive value. 3.2% of samples were negative by chemical UA but positive by microscopic UA. Of the samples with urine culture results available, 6.3% were negative by chemical UA but had clinically-significant positive urine cultures.CONCLUSIONS:
Reflex testing of microscopic UA and/or urine culture dependent from chemical UA results provides a feasible opportunity to reduce unnecessary testing.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones Urinarias
/
Orina
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Urinálisis
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Flujo de Trabajo
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Enfermedades Renales
Tipo de estudio:
Diagnostic_studies
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Observational_studies
/
Prognostic_studies
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Risk_factors_studies
Límite:
Adolescent
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Adult
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Aged
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Aged80
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Child
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Child, preschool
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Humans
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Infant
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Middle aged
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Newborn
Idioma:
En
Revista:
J Appl Lab Med
Año:
2020
Tipo del documento:
Article
País de afiliación:
Canadá