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Protocol for a multinational risk-stratified randomised controlled trial in paediatric Crohn's disease: methotrexate versus azathioprine or adalimumab for maintaining remission in patients at low or high risk for aggressive disease course.
Harris, Rachel E; Aloi, Marina; de Ridder, Lissy; Croft, Nicholas M; Koletzko, Sibylle; Levine, Arie; Turner, Dan; Veereman, Gigi; Neyt, Mattias; Bigot, Laetitia; Ruemmele, Frank M; Russell, Richard K.
Afiliación
  • Harris RE; Department of Paediatric Gastroenterology, Royal Hospital for Children Glasgow, Glasgow, UK.
  • Aloi M; Paediatric Gastroenterology and Liver Unit, Sapienza University of Rome, Roma, Lazio, Italy.
  • de Ridder L; Paediatrics, Erasmus MC/Sophia Childrens Hospital, Rotterdam, The Netherlands l.deridder@erasmusmc.nl.
  • Croft NM; Department of Paediatric Gastroenterology, Barts and The London School of Medicine and Dentistry, London, UK.
  • Koletzko S; Pediatric Gastroenterology and Hepatology, Dr. V. Hauner Children's Hospital, Munich, Germany.
  • Levine A; Department of Pediatrics, Collegium Medicum University of Warmia and Mazury, Olsztyn, Poland.
  • Turner D; Edith Wolfson Medical Center, Tel Aviv University, Tel Aviv, Israel.
  • Veereman G; Department of Paediatric Gastroenterology, Hebrew University of Jerusalem, Jerusalem, Israel.
  • Neyt M; Pediatric GI, UZBrussels-VUB, Brussels, Belgium.
  • Bigot L; Free University Brussels, University Hospital, Brussels, Belgium.
  • Ruemmele FM; ME-TA Medical Evaluation and Technology Assessment, Merendree, Belgium.
  • Russell RK; PIBD-Net, Hôpital universitaire Necker-Enfants malades, Paris, Île-de-France, France.
BMJ Open ; 10(7): e034892, 2020 07 01.
Article en En | MEDLINE | ID: mdl-32611737
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Azatioprina / Enfermedad de Crohn / Metotrexato / Adalimumab / Inmunosupresores / Antiinflamatorios Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Ethics Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: BMJ Open Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Azatioprina / Enfermedad de Crohn / Metotrexato / Adalimumab / Inmunosupresores / Antiinflamatorios Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Ethics Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: BMJ Open Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido