An overview of nanomedicines for neuron targeting.
Nanomedicine (Lond)
; 15(16): 1617-1636, 2020 07.
Article
en En
| MEDLINE
| ID: mdl-32618490
ABSTRACT
Medical treatments of neuron-related disorders are limited due to the difficulty of targeting brain cells. Major drawbacks are the presence of the blood-brain barrier and the lack of specificity of the drugs for the diseased cells. Nanomedicine-based approaches provide promising opportunities for overcoming these limitations. Although many previous reviews are focused on brain targeting with nanomedicines in general, none of those are concerned explicitly on the neurons, while targeting neuronal cells in central nervous diseases is now one of the biggest challenges in nanomedicine and neuroscience. We review the most relevant advances in nanomedicine design and strategies for neuronal drug delivery that might successfully bridge the gap between laboratory and bedside treatment in neurology.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Preparaciones Farmacéuticas
/
Nanopartículas
Idioma:
En
Revista:
Nanomedicine (Lond)
Año:
2020
Tipo del documento:
Article
País de afiliación:
España