Unusual Presentations of Primary and Metastatic Adenoid Cystic Carcinoma Involving the Skin.
Am J Dermatopathol
; 42(12): 967-971, 2020 Dec.
Article
en En
| MEDLINE
| ID: mdl-32618709
Adenoid cystic carcinoma (ACC) is most commonly seen in the salivary glands but may occur at other sites. Primary or metastatic involvement of the skin is unusual. We report 2 cases of ACC with unusual presentation. In the first case, a 55-year-old woman presented with a cutaneous lesion on the right shin, and final pathology showed ACC. An extracutaneous origin was excluded by clinical and imaging studies. In the second case, a 49-year-old woman presented with a nodule on the breast, and biopsy confirmed high-grade ACC (>30% solid areas). She underwent lumpectomy and subsequent mastectomy after recurrence. Sixteen months after the initial diagnosis of ACC of the breast, distant metastases at multiple sites, including the skin, were identified. This report will increase awareness of these rare presentations of cutaneous ACC and allow correct diagnosis and appropriate management of such cases.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Cutáneas
/
Neoplasias de la Mama
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Carcinoma Adenoide Quístico
Tipo de estudio:
Prognostic_studies
Límite:
Female
/
Humans
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Middle aged
Idioma:
En
Revista:
Am J Dermatopathol
Año:
2020
Tipo del documento:
Article
Pais de publicación:
Estados Unidos