Silver-Catalyzed C-H Aryloxydifluoromethylation and Arylthiodifluoromethylation of Heteroarenes.
Org Lett
; 22(14): 5451-5455, 2020 07 17.
Article
en En
| MEDLINE
| ID: mdl-32643379
The oxidative C-H aryloxydifluoromethylation and arylthiodifluoromethylation of heteroaromatic compounds through the decarboxylation of easily accessible aryloxydifluoroacetic acids and arylthiodifluoroacetic acids, respectively, are disclosed. These reactions are promoted by the combination of catalytic AgNO3 and Selectfluor or K2S2O8 to give ArOCF2- and ArSCF2-substituted heteroaromatic compounds in moderate to high yields.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2020
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
Estados Unidos