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The benefit of elobixibat in chronic constipation is associated with faecal deoxycholic acid but not effects of altered microbiota.
Misawa, Noboru; Higurashi, Takuma; Takatsu, Tomohiro; Iwaki, Michihiro; Kobayashi, Takashi; Yoshihara, Tsutomu; Ashikari, Keiichi; Kessoku, Takaomi; Fuyuki, Akiko; Matsuura, Tetsuya; Ohkubo, Hidenori; Usuda, Haruki; Wada, Koichiro; Naritaka, Nakayuki; Takei, Hajime; Nittono, Hiroshi; Matsumoto, Mitsuharu; Honda, Akira; Nakajima, Atsushi; Camilleri, Michael.
Afiliación
  • Misawa N; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.
  • Higurashi T; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.
  • Takatsu T; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.
  • Iwaki M; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.
  • Kobayashi T; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.
  • Yoshihara T; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.
  • Ashikari K; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.
  • Kessoku T; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.
  • Fuyuki A; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.
  • Matsuura T; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.
  • Ohkubo H; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.
  • Usuda H; Department of Pharmacology, Shimane University Faculty of Medicine, Izumo, Japan.
  • Wada K; Department of Pharmacology, Shimane University Faculty of Medicine, Izumo, Japan.
  • Naritaka N; Junshin Clinic Bile Acid Institute, Tokyo, Japan.
  • Takei H; Junshin Clinic Bile Acid Institute, Tokyo, Japan.
  • Nittono H; Junshin Clinic Bile Acid Institute, Tokyo, Japan.
  • Matsumoto M; Dairy Science and Technology Institute, Kyodo Milk Industry Co. Ltd, Tokyo, Japan.
  • Honda A; Gastroenterology, Tokyo Medical University Ibaraki Medical Center, Inashiki, Japan.
  • Nakajima A; Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine, Yokohama, Japan.
  • Camilleri M; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Aliment Pharmacol Ther ; 52(5): 821-828, 2020 09.
Article en En | MEDLINE | ID: mdl-32687674
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiazepinas / Estreñimiento / Defecación / Ácido Desoxicólico / Dipéptidos / Microbiota Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Aliment Pharmacol Ther Asunto de la revista: FARMACOLOGIA / GASTROENTEROLOGIA / TERAPIA POR MEDICAMENTOS Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiazepinas / Estreñimiento / Defecación / Ácido Desoxicólico / Dipéptidos / Microbiota Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Aliment Pharmacol Ther Asunto de la revista: FARMACOLOGIA / GASTROENTEROLOGIA / TERAPIA POR MEDICAMENTOS Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido