Naloxegol rescue with methylnaltrexone highly effective.
BMJ Support Palliat Care
; 10(3): 316-317, 2020 Sep.
Article
en En
| MEDLINE
| ID: mdl-32709705
ABSTRACT
Opioid-induced constipation (OIC) is common and can significantly affect quality of life. Naloxegol and methylnaltrexone are peripherally acting µ-opioid receptor antagonists (PAMORAs) which are effective for the management of OIC. We report on a case in the palliative care setting where a patient with established OIC had an inadequate response to naloxegol but an effective and immediate response to methylnaltrexone at the dose recommended for her weight. This is the first reported case of two PAMORAs used concomitantly.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cuidados Paliativos
/
Estreñimiento Inducido por Opioides
/
Analgésicos Opioides
/
Naltrexona
/
Antagonistas de Narcóticos
Tipo de estudio:
Etiology_studies
Aspecto:
Patient_preference
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
BMJ Support Palliat Care
Año:
2020
Tipo del documento:
Article
País de afiliación:
Reino Unido